The British "Nature" magazine recently published a new study on neurodegenerative diseases. American scientists have discovered an autoimmune feature of patients with Parkinson's disease: the patient's immune system is "confused" to attack brain neurons. This new discovery may bring new insights into the causes of Parkinson's disease.

Parkinson's disease is a common neurodegenerative disease. Although scientists have recognized the most important pathological changes in this disease, the exact cause of this change has not been known so far. It is currently believed that genetic factors, environmental factors, and ageing may all be involved.

It is generally believed that neurodegenerative diseases have no autoimmune features, but previous genetic studies have found that Parkinson's disease is associated with major histocompatibility complex (MHC) gene variants. MHC proteins bind to processed protein fragments and present these proteins on the cell surface, allowing them to be sampled by immune cells. Most fragments are ignored by the immune system, but some cause T cell responses.

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