Release date: 2016-02-25

The human brain has obvious peaks and valleys, which are easy to explain from an evolutionary point of view, but it is difficult to understand the details of the formation of the brain folds. According to the Harvard University website, researchers at the school collaborated with Finnish and French scientists to prove that although many molecular processes are important, the brain instability is the mechanism of mechanical instability of the cortical deformation.

From an evolutionary perspective, the reason why human brain folds are like this is to install a larger cortex in a small space, reduce the length of neuronal branches, and improve cognitive function. When humans are pregnant for about 20 weeks, the fetal brain begins to wrinkle, and until about one and a half years of birth, the brain folds are completed. L. Maha Dewen, a professor of applied mathematics at the School of Engineering and Applied Science at Harvard University, found that during brain development, the expansion of the cortex relative to the underlying white matter causes stress and mechanical instability. Stabilization causes it to form local folds.

The researchers published a paper in the journal Nature and Physics that they used the brain data of human fetuses to test the theory. According to the 3D magnetic resonance image, they made a three-dimensional colloidal model of a smooth fetal brain by 3D printing, applying a thin layer of elastic glue on the surface, imitating the cortex, and then immersing the colloidal brain into a layer that can be The solution absorbed by the gel causes the outer layer to swell relative to the inside, simulating the expansion of the cortex. Within a few minutes, the pressure causes the colloid brain to form folds, and the folds and shapes are like a real brain.

The similarity of the expansion surprised the researchers. “When I put the model in solution, I knew that it would wrinkle, but I didn’t expect it to be so similar. It looked like a real brain.” The paper co-author and postdoctoral researcher Zheng Junyong said, “The shape of the human brain is folds.” The direction provides a reference. Our model is identical in shape and curvature to the human brain, so the resulting folds are very consistent with the real fetal brain."

The function is usually related to the structure, so understanding how the brain folds form, helps reveal the inner workings of the brain, and clarifies the brain-related diseases. Zheng Junyong also pointed out that the brains of people and people are not exactly the same, but as healthy people, the main folds should be the same. If a part of the brain develops incorrectly, or the entire brain shape is disturbed, it may not be able to form major folds at the correct position, resulting in brain dysfunction.

Source: Technology Daily

Vtm Sampling Tube With Swab

[Sample requirements]
The collected nasopharyngeal swab samples should be transported at 2°C to 8°C and sent for inspection immediately, and the sample delivery and storage time should not exceed 48 hours.

[Testing method]
1. Before sampling, mark the relevant sample information on the label of the sampling tube.
2. According to different sampling requirements, use a sampling swab to sample in the nasopharynx.
3. The specific sampling methods are as follows:
a) Nasal swab: Gently insert the swab head into the nasal palate, stay for a while and then slowly turn to exit. Wipe the other nostril with another swab, immerse the swab head in the sampling solution, and discard the tail.

b) Pharyngeal swab: Wipe bilateral pharyngeal tonsils and posterior pharyngeal wall with a swab, also immerse the swab head in the sampling solution, and discard the tail.

4. Quickly put the swab into the sampling tube.
5. Break the part of the sampling swab higher than the sampling tube, and tighten the tube cover.
6. Freshly collected clinical specimens should be transported to the laboratory within 48 hours at 2°C to 8°C.

[Explanation of test results]
After the sample is collected, the sampling solution turns slightly yellow, which will not affect the nucleic acid test result.

[Limitations of the test method]
1. For samples that are seriously contaminated due to improper storage after collection, the final test results will be affected.
2. If the sample is not stored at the specified temperature, the final test result will be affected.

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