10 truths about cancer cells

Cancer cells are abnormal cells that can rapidly regenerate and regenerate. This unconstrained cell growth rate promotes the formation and deterioration of tissue blocks and tumors. Tumors continue to grow, some of which are called malignant tumors, and they can spread from one location to another. Cancer cells and normal cells have different manifestations in many places. Cancer cells do not biologically age, can continue to divide, and do not respond to signals of cell termination.

The following ten interesting truths about cancer cells may surprise you.

1. There are more than 100 types of cancer.

There are many types of cancer, and these cancers may evolve into any type of somatic cell, usually named after the organ, tissue or cell of the lesion. The most common type of cancer is a malignant tumor or skin cancer, which develops lesions in the epithelial tissue that covers the outside of the body and aligns body organs, blood vessels, and cavities. Sarcomas are formed in muscles, bones, and soft connective tissue, including: adipose tissue, blood vessels, lymphatic vessels, tendons, and ligaments. A cancer in which bone marrow cells producing white blood cells develop lesions is called leukemia. Lymphoma is a white blood cell, that is, a lymphocyte has a lesion. Such cancers affect B cells and T cells.

2. Some viruses can breed cancer cells

There are many factors that contribute to the development of cancer cells, including exposure to chemicals, radiation, ultraviolet light, and chromosome replication errors.

In addition, viruses can also cause cancer cells by altering genes. It is estimated that cancer viruses account for 15% to 20% of all cancer types. These viruses achieve the goal of altering normal cells by combining their own genetic material with the DNA of the host cell. Viral genes regulate cell growth and allow cells to undergo abnormal growth rates. Burkitt's lymphoma is associated with Epstein-Barr virus, which can cause liver cancer, and human papillomavirus can cause cervical cancer.

3. About one-third of cancers are preventable.

According to the World Health Organization, about 30% of cancers are preventable. It is estimated that only 5-10% of cancers are caused by genetic defects. Other cancers are associated with environmental pollution, infections, and lifestyles (smoking, unhealthy eating habits, lack of exercise). The most effective way to prevent cancer is to quit smoking. About 70% of lung cancer is caused by smoking.

4. Cancer cells require extreme sugar

Cancer cells require more glucose to grow than normal cells. When cells breathe, they need glucose, a simple sugar, to produce energy. In order to continue to divide, cancer cells absorb sugar very quickly. The way these cancer cells gain energy is not only glycolysis, the process by which sugar is broken down to produce energy. Tumor cell mitochondria also provide the energy needed for abnormal growth of cancer cells. Mitochondria is an enhanced version of the energy source that also makes tumor cells more resistant to chemotherapy.

5. Cancer cells lurk in the body

Cancer cells are hidden around healthy cells to avoid the immune system in the body. For example, some tumors secrete a protein secreted by a lymph node that causes the tumor to turn the outer layer into a substance similar to lymphoid tissue. These tumors look like healthy tissues rather than cancerous tissues. As a result, immune cells cannot find that they are harmful substances, allowing them to grow and spread freely in the body. Other cancer cells avoid chemotherapy drugs through the compartments hidden in the body. Some leukemia cells avoid treatment by hiding inside the bone.

6. Cancer cells can change shape

Cancer cells change to avoid the defenses of the immune system and prevent radiation and chemotherapy. Taking cancerous epithelial cells as an example, they began to mimic healthy cells with a fixed morphology, which later evolved to mimic loose connective tissue. Scientists liken this process to snakeskin, the ability to change morphology thanks to the inactivation of molecular switches, tiny ribonucleic acids, which have the ability to regulate gene expression. When some tiny ribonucleic acids are inactivated, the tumor cells gain the ability to change morphology.

7. Cancer cell division is out of control and produces extra daughter cells

Cancer cells can be genetically or mutated to disrupt the regenerative properties of the cells. Normal cells can produce two daughter cells through mitosis, but cancer cells can divide into three to four daughter cells. New cancer cells may lose or add new chromosomes during the process of division. Most malignant tumors have cells that have lost their chromosomes.

8. Leaves the blood vessels, cancer cells will not survive

One of the warning signs of cancer is the rapid increase in new blood vessels (ie, angiogenesis) in the body. Tumors require nutrients provided by blood vessels to grow. The vascular endothelium is responsible for both normal angiogenesis and tumor angiogenesis. Cancer cells send signals to the nearest healthy cells, affecting them, and then generating new blood vessels to supply nutrients to the cancer cells. Studies have shown that if angiogenesis is prevented, the tumor will stop growing.

9. Cancer cells can spread from across regions

Cancer cells can spread across regions through the bloodstream or lymphatic system. When cancer cells activate receptors in the blood vessels, they can withdraw from the blood circulation and spread into tissues and organs. Cancer cells release chemical signals called chemokines that cause an immune response that allows them to pass through blood vessels into surrounding tissues.

10. Cancer cells can avoid programmed cell death

When the DNA of normal cells is damaged, tumor suppressor proteins are released to cause programmed cell death or apoptosis. However, due to genetic mutations, cancer cells cannot detect DNA damage and therefore cannot be self-destructive.

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