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The scientific community has also been looking for new ways to reduce blood pressure. Recently, German scientists have developed a new type of device that can lower blood pressure by stimulating the nerves of the neck. This device is expected to replace antihypertensive drugs, especially for patients with very high blood pressure.
New implantable devices can effectively lower blood pressure "This implantable device, whether used alone or in combination with drugs, can lower blood pressure," said Dennis Plachta, a microengineer at the University of Freiburg, Germany. "It's not just for those who can't." Patients who take medication (or do not use medication) offer a second chance and a simultaneous solution for existing medications."
Plachta and his team developed a micromechanical band that wraps around the vagus nerve, a nerve in the neck that exchanges key physiological information between the brain and other vital organs, including the heart. With a 20 mm length, a set of electrodes is placed in the nerve-related area to cause blood pressure changes through specific stimulation. The researchers tested the implants in five adult rats and found that a certain stimulation pattern reduced the blood pressure of these mice by 4% without major side effects.
Plachta said that the device's implantation into the human body will be similar to the existing vagus nerve stimulation for device implantation during epilepsy. The first is to make a small incision in the left neck, the surgeon gently wraps the electrode around the nerve, and the devices are then connected to a capsule containing a pulse generator that is implanted under the chest muscle through the left inferior incision. The entire procedure takes about an hour and a half or less.
Prospects <br> <br> chairman-elect of the American Society of Hypertension John Bisognano said the latest work progress in the field of microsurgery and microelectronics in impressive, and has broad application prospects.
Bisognano is a cardiologist who runs a refractory hypertension treatment clinic at the University of Rochester Medical Center in New York. He knows the patient's need for more treatment options. He said that all of his patients are taking a variety of antihypertensive drugs, and some people have some side effects that make drug treatment unsustainable. "The worst thing is that their blood pressure is still high, which means they are at high risk of stroke, heart failure, kidney failure," he said.
Implanted electronic devices have been used for many years to control bodily functions, and perhaps the most well-known is the pacemaker used by heart patients. In addition, electronic devices are also used to control Parkinson's disease, as well as to control some mental illnesses in the laboratory, and even for unrelated diseases such as bladder dysfunction and rheumatoid arthritis.
Kristoffer Famm, vice president of bioinformatics research and development at GlaxoSmithKline, co-authored a paper with others in this new field last year – he and his academic colleagues called the field electroceuticals. The company has invested $50 million in companies that develop this technology.
Bisognano said that nerve stimulation is a logical mechanism for controlling blood pressure. It is well known that the nervous system can regulate the pressure of the body's arteries and control the strength and frequency of the heart contraction. But with the latest advances in technology, this knowledge can come in handy to develop device-based therapies. Previously, Bisognano had successfully stimulated the carotid artery to successfully lower blood pressure through an experimental implant – the implant was completely different from the design of the Plachta team.
Using this new device developed by the Plachta team, blood pressure in rats was reduced in less than 5 seconds after stimulation of the rat nerve. Plachta said he and his colleagues are also developing a smart version of the device that is more versatile, capable of detecting blood pressure and responding to physical needs in real time. Drugs can't adapt to patient activity, and smart implants can. This will provide a "hyper-need" high blood pressure therapy.
New microelectronic implantable device can effectively lower blood pressure
Under current medical conditions, hypertension is a lifelong disease that cannot be cured. Patients can only control blood pressure, thereby reducing and reducing mortality, preventing and reducing the occurrence of cardiovascular and cerebrovascular complications. However, up to 30% of hypertensive patients cannot be adequately treated with drugs, and some patients who take medication may experience side effects such as fatigue and dizziness.