March 24th is the 22nd World Tuberculosis Day. The theme of this year’s Tuberculosis Day is “Social Work Together to Eliminate Tuberculosis Hazardsâ€. In 2016, WHO reported 10.4 million people worldwide with tuberculosis. In 2015, 1.8 million died of tuberculosis. Today, tuberculosis has become the world's largest infectious disease killer. This disease is deeply rooted in people with limited human rights and dignity. in. In recent years, scientists have made many breakthroughs in the field of tuberculosis research. This article has compiled and summarized this article. Nat Genet: Global scientists work together to make a major breakthrough in tuberculosis research! Tuberculosis is a disease that threatens the public health of the world. It usually takes several months to treat patients. Until now, there is no effective vaccine against tuberculosis for prevention. Many different types of M. tuberculosis exist in many parts of the world. And it has a different geographical distribution, only the so-called strain lineage 4 exists in all continents. Of the 10 million new infected and 2 million deaths each year, most of the individuals are due to such strains. And infection. Recently, a research report published in the international journal Nature Genetics, 75 scientists from 56 research institutions around the world conducted a joint study to analyze the genetic composition of Mycobacterium tuberculosis from thousands of tuberculosis patients. The researchers found that the M. tuberculosis lineage type 4 can be genetically divided into multiple sub-lineages, some of which are distributed globally, while others are mainly limited by geographic distribution. The researchers point out that M. tuberculosis is often divided into globally distributed general-purpose strains and special strains that focus on local ecological environments; M. tuberculosis has unique properties that hardly alter their own antigens, and bacteria It can also be effectively recognized by the body's immune system. Once the body's strong immune response occurs, it will affect the health of the lungs, thereby promoting the cough of infected people, and M. tuberculosis can also effectively spread between people. mBio eLife: A small 3D sphere model can effectively fight against tuberculosis Recently, researchers from institutions such as the University of Southampton have developed a new 3D model for investigating human body infections in the laboratory. In this paper, researchers have used electrostatic packaging technology to create a small 3D sphere that can In human cells infected with Mycobacterium tuberculosis (TB), conditions that closely reflect the body's disease are produced. Related studies are published in international journals mBio and eLife. The new 3D sphere can help researchers delve into the events that occur when the body is infected with tuberculosis, and researchers hope to develop new antibiotic therapies and vaccines against tuberculosis based on the results of this study. Researcher Paul Elkington said that this is a major research advance in the field of tuberculosis research. This 3D sphere can be created in a collagen matrix so that it looks very similar to human lungs, while at the same time producing a The special environment allows the treatment of patients' special antibiotics to effectively kill the bacteria that cause tuberculosis. This is currently not possible in other 2D model systems. This new system will speed up researchers' search for new treatments for human tuberculosis and the development of vaccines. . Antioxidants Vitamins,Antioxidant Vitamins Tablets,Rubber Antioxygen,Antioxidants Free Radicals SHANDONG BAISHENG BIOTECHNOLOGY CO., LTD , https://www.baishengbioproducts.com