Latest research: CRISPR/dCas9 technology awakens sleeping tumor suppressor genes

According to a recent development by Australian researchers, let our genes destroy cancer cells from the body so that they can cure cancer without taking medicine. The researchers used genetic editing technology CRISPR/dCas9 to awaken key tumor suppressor genes to destroy cancer from within. The research team focused on applying this technology to breast and lung cancer cells, as well as the potential effects on gastric tumor cells.

"We have cancerous cells every day in our body, but the body has a very efficient DNA damage recognition system that will repair or perform a self-destruction process after the injury is discovered," said Dr. Benjamin Garcia-Bloj.

Tumor suppressor genes can check cells to ensure that the cells do not have any damage and mutations, and there is no loss of growth, so these genes are the key to the body to clear the cancer cells to achieve self-healing.

Latest research: CRISPR/dCas9 technology awakens sleeping tumor suppressor genes

"If you can reactivate or say 'wake up' these tumor suppressor genes in the future, it would be great to let them do the work of treating the disease. This way, you can treat the disease without taking medicine, which is used in traditional cancer treatment methods. Drugs often have an adverse effect on the body,” Dr. Garcia-Bloj said.

"There are some mechanisms in the cell that prevent normal cells from becoming cancer cells, but some tumor suppressor genes are silenced after people get cancer. The treatment we developed allows cells to remember how to activate these mechanisms to stop the spread of cancer. ."

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