Protease Inhibitor Aprotinin 100 Kiu/Mg CAS: 9087-70-1

October 26, 2018

Model NO.: Aprotinin
Model No.: 9087-70-1
Shipping Method: EMS, DHL, FedEx, UPS
Characters: White Powder
Delivery Detail: 3-7days After Payment
Trademark: JCJCHEM
Transport Package: as Your Requiry
Specification: >99%
Origin: China
HS Code: 293299909
Model NO.: Aprotinin
Model No.: 9087-70-1
Shipping Method: EMS, DHL, FedEx, UPS
Characters: White Powder
Delivery Detail: 3-7days After Payment
Trademark: JCJCHEM
Transport Package: as Your Requiry
Specification: >99%
Origin: China
HS Code: 293299909
Protease Inhibitor Aprotinin 100 KIU/MG CAS: 9087-70-1

Description:

Aprotinin, also known as bovine pancreatic trypsin inhibitor, BPTI (Trasylol, Bayer) is a protein, that is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots. The aim in its use is to decrease the need for blood transfusions during surgery, as well as end-organ damage due to hypotension (low blood pressure) as a result of marked blood loss. The drug was temporarily withdrawn worldwide in 2007 after studies suggested that its use increased the risk of complications or death; after this was confirmed by follow-up studies, Trasylol was entirely and permanently withdrawn in May 2008, except - at least for the time being - for very restricted research use.

Basic info:

Chemical name: Aprotinin
M. Wt: 6511.48
Formula: C284H432N84O79S7
Sequence: RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
(Modifications: Disulfide bridge: 5-55, 14-38, 30-51)
Storage: Store at +4°C
CAS Number: 9087-70-1
Appearance: white powder

COA:
 
Product name Aprotinin
CAS No. 9087-70-1 Outer Packing
25KG/Foil bag
 
Production date 170712 Shelf life
190711
Standard adopted enterprise standard
Items of analysis Specification Results
Appearance
 		 White or Off-white
 		 Complies
Characteristics Powder 80 mesh
Valence
100 KIU/mg
 
106
 
Moisture
≤ 7.0%
5.1%
Ash Content
≤ 6.0%
4.3%
Protein ≥ 65% 70.5%
Insoluble
≤ 1% 		< 0.5%

Total Plate Count
 
≤ 10000 CFU/g
 
930 CFU/g
 

E.Coli
 
≤ 0.4 CFU/g
 
0.1 CFU/g
 

Mold
 
≤ 25 CFU/g
 
<10 CFU/g
 

Yeast
 
≤ 25 CFU/g
 
<10 CFU/g
 

Pathogenic Bacteria
 
Negative
 
Negative
 
Conclusion Qualified

Mechanism of action:

Aprotinin inhibits several serine proteases, specifically trypsin, chymotrypsin and plasmin at a concentration of about 125,000 IU/ml, and kallikrein at 300,000 IU/ml. Its action on kallikrein leads to the inhibition of the formation of factor XIIa. As a result, both the intrinsic pathway of coagulation and fibrinolysis are inhibited. Its action on plasmin independently slows fibrinolysis.

How to use aprotinin:

Use aprotinin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with aprotinin. Talk to your pharmacist if you have questions about this information.
Aprotinin is administered as an intravenous (IV; into a vein) injection only in a medical setting.
If you miss a dose of aprotinin, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use aprotinin.

Protease Inhibitor Aprotinin 100 Kiu/Mg CAS: 9087-70-1

Related product list:
 
Product name CAS number
Dexketoprofen trometamol 156604-79-4
(S)-(+)-Ketoprofen 22161-81-5
Sodium octadecyl fumarate 4070-80-8
Cinnamyl acetate  103-54-8
Cetirizine hydrochloride 83881-52-1
Tirofiban hydrochloride monohydrate  150915-40-5 
TERAZOSIN HYDROCHLORIDE 63074-08-8 
Cyproheptadine hydrochloride  41354-29-4 
   
Naftifine hydrochloride 65473-14-5 
Ritodrine hydrochloride  23239-51-2 
Flavoxate hydrochloride  3717-88-2 
Fexofenadine hydrochloride  153439-40-8
DULOXETINE HYDROCHLORIDE 136434-34-9 
   
Ambroxol  18683-91-5 
   
   
Halofuginone 55837-20-2 
 Reserpine  50-55-5 
   
   
Choline chloride  67-48-1
Loratadine  Loratadine 

Our  Advantage: 

   High quality with competitive price: 
   1)Standard: Enterprise Standard
   2)All Purity:>=99%
   3)We are manufacturer and can provide high quality products with factory price. 

   Fast and safe delivery
   1)Parcel can be sent out in 24 hours after payment. Tracking number available
   2)Secure and discreet shipment. Various transportation methods for your choice. 
   3)Customs pass rate: >=99%
   4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring. 

   We have clients throughout the world. 
   1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
   2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility. 
   3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

Please feel free to contact me:

Tel: +8618872220738 Protease Inhibitor Aprotinin 100 KIU/MG CAS: 9087-70-1

Description:

Aprotinin, also known as bovine pancreatic trypsin inhibitor, BPTI (Trasylol, Bayer) is a protein, that is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots. The aim in its use is to decrease the need for blood transfusions during surgery, as well as end-organ damage due to hypotension (low blood pressure) as a result of marked blood loss. The drug was temporarily withdrawn worldwide in 2007 after studies suggested that its use increased the risk of complications or death; after this was confirmed by follow-up studies, Trasylol was entirely and permanently withdrawn in May 2008, except - at least for the time being - for very restricted research use.

Basic info:

Chemical name: Aprotinin
M. Wt: 6511.48
Formula: C284H432N84O79S7
Sequence: RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
(Modifications: Disulfide bridge: 5-55, 14-38, 30-51)
Storage: Store at +4°C
CAS Number: 9087-70-1
Appearance: white powder

COA:
 
Product name Aprotinin
CAS No. 9087-70-1 Outer Packing
25KG/Foil bag
 
Production date 170712 Shelf life
190711
Standard adopted enterprise standard
Items of analysis Specification Results
Appearance
 		 White or Off-white
 		 Complies
Characteristics Powder 80 mesh
Valence
100 KIU/mg
 
106
 
Moisture
≤ 7.0%
5.1%
Ash Content
≤ 6.0%
4.3%
Protein ≥ 65% 70.5%
Insoluble
≤ 1% 		< 0.5%

Total Plate Count
 
≤ 10000 CFU/g
 
930 CFU/g
 

E.Coli
 
≤ 0.4 CFU/g
 
0.1 CFU/g
 

Mold
 
≤ 25 CFU/g
 
<10 CFU/g
 

Yeast
 
≤ 25 CFU/g
 
<10 CFU/g
 

Pathogenic Bacteria
 
Negative
 
Negative
 
Conclusion Qualified

Mechanism of action:

Aprotinin inhibits several serine proteases, specifically trypsin, chymotrypsin and plasmin at a concentration of about 125,000 IU/ml, and kallikrein at 300,000 IU/ml. Its action on kallikrein leads to the inhibition of the formation of factor XIIa. As a result, both the intrinsic pathway of coagulation and fibrinolysis are inhibited. Its action on plasmin independently slows fibrinolysis.

How to use aprotinin:

Use aprotinin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with aprotinin. Talk to your pharmacist if you have questions about this information.
Aprotinin is administered as an intravenous (IV; into a vein) injection only in a medical setting.
If you miss a dose of aprotinin, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use aprotinin.

Protease Inhibitor Aprotinin 100 Kiu/Mg CAS: 9087-70-1

Related product list:
 
Product name CAS number
Dexketoprofen trometamol 156604-79-4
(S)-(+)-Ketoprofen 22161-81-5
Sodium octadecyl fumarate 4070-80-8
Cinnamyl acetate  103-54-8
Cetirizine hydrochloride 83881-52-1
Tirofiban hydrochloride monohydrate  150915-40-5 
TERAZOSIN HYDROCHLORIDE 63074-08-8 
Cyproheptadine hydrochloride  41354-29-4 
   
Naftifine hydrochloride 65473-14-5 
Ritodrine hydrochloride  23239-51-2 
Flavoxate hydrochloride  3717-88-2 
Fexofenadine hydrochloride  153439-40-8
DULOXETINE HYDROCHLORIDE 136434-34-9 
   
Ambroxol  18683-91-5 
   
   
Halofuginone 55837-20-2 
 Reserpine  50-55-5 
   
   
Choline chloride  67-48-1
Loratadine  Loratadine 

Our  Advantage: 

   High quality with competitive price: 
   1)Standard: Enterprise Standard
   2)All Purity:>=99%
   3)We are manufacturer and can provide high quality products with factory price. 

   Fast and safe delivery
   1)Parcel can be sent out in 24 hours after payment. Tracking number available
   2)Secure and discreet shipment. Various transportation methods for your choice. 
   3)Customs pass rate: >=99%
   4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring. 

   We have clients throughout the world. 
   1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
   2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility. 
   3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

Please feel free to contact me:

Tel: +8618872220738

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