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The study found that multiple pathogens infect humans are more harmful
According to a recent study, the diverse nature of parasite genetics means that people are often at risk of being infected with multiple pathogens, which will make infections worse over time.
Manson's Schistosomiasis is a type of aquatic parasite that has two types of hosts: snails and humans. When the parasite eggs in the infected person are produced, they will enter the water in some way to infect the snail. After that, the parasite will leave the snail into the water and finally infect the body through the skin.
In order to understand the underlying causes of the parasite's threat to the host, researchers from Purdue University studied two different parasites.
The results showed that the symptoms of the mice infected with the two parasites were comparable to those of the mice infected with one of the more potent parasites, but were significantly heavier than the mice infected with the other lighter parasite. The results are published in the latest issue of Parasitology.
The infection of Manson's Schistosomiasis initially causes people to experience symptoms of weakness for several weeks and then enters the stage of replication. Most of the eggs leave the body, but a small part of them enter the liver or the intestines trigger an inflammatory reaction. This can lead to symptoms such as sweating, diarrhea, and enlarged abdominal cavity.
In addition, the authors believe that parasitic infections with different genetic backgrounds may aggravate the symptoms of the human host and also prolong the parasitic cycle in the snail host. An understanding of this mechanism will help develop targeted treatment options in the future.