China has achieved the latest breakthrough in the treatment of type 1 diabetes November 08, 2016 Source: Science Network Recently, the reporter learned from the 307 Hospital that the team led by the researcher of the Institute of Immunology and the famous blood immunologist, Yong Yongzhi, has been working for more than 20 years and successfully developed the first co-stimulation pathway based on B7-CD28/CTLA4 in the world. A new therapeutic gene vaccine for the treatment of type 1 diabetes. This is the latest breakthrough in the field of type I diabetes biotherapy in China. It is an original achievement with China's completely independent intellectual property rights. It has successively obtained “three-party†patents from China, the United States and the European Union. At the same time, the Japanese invention patent applied for is in the process of replying to the review. The “three-party patent†is one of the standards recognized by the international community to evaluate whether a country has reached an innovative country, and it can more truly reflect the quality and competitiveness of technology and output. It is reported that China is the country with the largest number of diabetes patients in the world, with a total of 110 million, of which type I diabetes (T1DM), also known as insulin-dependent diabetes, totals nearly 10 million. T1DM is a kind of metabolic disease, which belongs to the category of autoimmune diseases. Its pathological features are abnormal autoimmune cellular and humoral immune responses, leading to the reduction of islet β cell damage and insulin secretion, which seriously endangers human health. The effective treatment of T1DM is still a long-term supplement for insulin or insulin analogues. From the previous research data, the therapeutic gene vaccine developed by Yan Yongzhi's team can reduce the long-term dependence of patients on insulin, reduce the side effects caused by long-term injection of insulin, significantly reduce medical costs, and significantly reduce the frequency of treatment. At present, the team is actively promoting the application of the genetic vaccine patent to transform the society as soon as possible.
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