——A self-innovation forging protection brigade of a pharmaceutical research institute of the Military Medical Research Institute of the Academy of Military Sciences

One day in early summer, the reporter went to the biological laboratory of a pharmaceutical research institute of the Military Medical Research Institute of the Academy of Military Sciences.

Here is a world of biology and chemistry. The conical flask is filled with the experimental table. The color of the liquid in the bottle is different, and the glassware of various shapes is everywhere.

It leads to a magical microcosm, where molecules and compounds are the objects of their dealings all year round. The most common equipment in the laboratory is a microscope: a polarizing microscope, an optical microscope, an electron microscope...

Under the microscope, there is a mission - this research institute is responsible for the medical protection of battlefield damage, special medicines and drug research for major diseases, and is an important force in the field of medical protection to safeguard the safety of the country and the military.

There is loyalty under the microscope. In the 60 years since its establishment, this research institute has overcome difficulties and achieved many major scientific research achievements in the world. It plays a key role in the critical moments of national emergency rescue and major epidemic prevention and control.

Surname military for war, forging battlefield medical protection shield

At night, the research building of a pharmaceutical research institute is still brightly lit. Suddenly, a whistle broke the silence of the night. A small team in camouflage uniform rushed out of the building and quickly assembled. Under the command of the commander, the team members quickly opened the standard carrying case group that they carried with them, and checked the drug reagents...

This is a routine emergency pull, and the emergency detachment of the institute is fully loaded and ready to be dispatched.

The surname army is fighting, and there is smoke in the laboratory. In the early days of the founding of New China, it was precisely to solve the medical protection problems in the complex battlefield environment of our army. The predecessor of the institute was formally established in 1958. A group of scientists gathered in this silent battlefield from all directions and launched a charge to the medical protection position.

At the beginning of the construction, they had no experience to follow. No equipment was available. There were no decent instruments. Some were just a few portable scales, broken alarm clocks and bottles and cans.

How to do? In the face of foreign strict technical blockade, they searched for clues from the open literature; lacked experimental equipment, and made their own drawings, and successively designed and produced experimental equipment such as special fume hood, liquid automatic diverting device and melting point measuring device.

In just one year, they took initial prevention measures in the key areas of protection, and launched protective measures such as military drinking water testing boxes and simple military food inspection boxes to achieve zero breakthrough in medical protection of our military. Then, they set a more ambitious goal: to build a medical protection system from point to point to meet the needs of actual combat.

Effective protection and treatment, the key is in medicine. In order to find the source of medicine, in those years, they went to the mountains, the islands, and even the uninhabited areas, collecting more than 5,000 kinds of prescriptions and Chinese herbal medicines, so that the protective drugs have a broad screening basis. Screening compounds is more complicated and time-consuming, and Su Ruibin, director of the institute, said that sometimes it is even more than 10,000 to find a target compound.

Step by step, thousands of miles, dripping water and long river. In that year, the research project with more than 40 scientific research achievements of the institute as an important component won the first national science and technology progress award in the field of medical and health. This also marks that China has a medical protective shield to maintain national security.

In recent years, they have always focused on the key research directions of military medical construction needs, and accelerated the connection between scientific research results and practical applications.

Formulate the national military standard system for the decontamination, diagnosis and treatment of the enactment system, research and development with a series of on-site rescue equipment; build China's first special drug raw material drug pilot and industrialization base, solve the problem of special drug protection under emergency conditions; overcome the battlefield The key problems in the "anti-inspection, treatment and treatment" of medicine have formed a new protective capability, and the results won the first prize of the National Science and Technology Progress Award.

Strengthening the country for the people and building a national security drug defense line

Going to the winter and spring, a flu pandemic swept the northern hemisphere, and outbreaks broke out in many places in China.

The flu virus is highly harmful. The Spanish flu 100 years ago has claimed nearly 40 million lives worldwide.

How to deal with possible major influenza epidemics? More than 10 years ago, the Institute took this as an important topic. After the SARS epidemic in 2003, Li Song, a researcher at the institute, led the team to look forward to the layout, using the influenza virus as a key research direction, and launched a pre-research on drugs.

A year later, the H5N1 bird flu epidemic occurred frequently throughout China. At that time, there was no self-produced anti-influenza medicine in China, and we contacted foreign pharmaceutical companies urgently. The answer was: 4 years later, we can supply it. This means that if there is a large-scale influenza epidemic in China within 4 years, 1.3 billion people will Faced with the dilemma of no medicine available.

It is related to national public health security, can't afford it! Slow!

Just at the moment of facing the "card neck", the institute took the initiative. Their self-developed anti-influenza drugs completed all preclinical work in a short period of time. Then, they assisted the country in building an anti-influenza drug production line and completed the national and military strategic reserve tasks.

Independent innovation, strengthening the country for the people. In 2009, when the bird flu hit, they once again created a miracle: increasing the drug production capacity by 30 times, completing the national reserve task in only 135 days, and saving 5.7 billion yuan for the country.

It is understood that at present, China has become one of the countries with the most abundant anti-influenza drugs and the strongest clinical treatment support ability, and has the ability to prevent and control influenza of various scales.

Independent innovation must win people. In the past, in order to retain Li Song, a postdoctoral tutor and researcher, Jiao Kefang not only recommended Li Song to take over as the team leader, but also proposed to retire immediately, so that Li Song has complete scientific autonomy. This stayed aside and made the later Chinese Academy of Engineering academician Li Song.

In recent years, the Institute has launched the “Talent Port Program” and the “Youth Talents Training Program”, selected scientific research seedlings, and let them take the lead in scientific research. Today, the institute has three academicians of the two academies, 30 people selected for the national talent project such as the 100 million talent project and the national 10,000 plan.

In the relay of generations of outstanding talents, the Institute has always aimed at the major diseases affecting public health security and the health of the people. It has spawned a large number of achievements for the benefit of the country: the development of new anti-filariasis drugs and anti-tuberculosis The new drug, the invention of the oral disease therapeutic drug with Chinese invention patent, launched the organophosphorus pesticide poisoning first aid special drug known as "anti-toxic god needle"......

Indifferent, adhering to the spirit of selfless and fearless spirit

In August 2015, a major fire and explosion accident occurred in Tianjin Port. At that time, the rescuers were moving toward the "most beautiful retrograde" in the core area of ​​the explosion, which touched thousands of netizens.

The researcher Wang Yongan was in the retrograde ranks. As a protection expert, he has to take the lead in the core of the explosion.

Dressed in heavy protective clothing and continuous high temperature work, Wang Yongan almost collapsed. However, after careful investigation, the principle of “non-incoming prevention, non-introduction, cross-regional disposal, and graded protection” has become the guiding principle for guiding rescue.

The mission is on the shoulders, selfless and fearless. The story of Wang Yongan is not a case.

That year, the institute was responsible for the production of an emergency drug. Due to the danger of the production process, the factory suddenly withdrew all the workers on the eve of the start of construction. How to do? Jiao Kefang and Xie Yunde, who were stationed in the pharmaceutical factory, resolutely assumed all the production tasks. More than 40 days later, when they delivered the qualified drugs to the troops on time, they were already tired of physical problems.

In the early days of the establishment of the institute, in order to develop reliable protective drugs as soon as possible, the scientific research personnel did not hesitate to take the test, and the cumulative number of participants in the test was more than 3,000, and the highest dose was 8 times that of clinical application.

Later, the scientific research conditions improved, and everyone no longer had to "test the poison", but sacrificed the spirit of dedication to pass on from generation to generation.

In the History Museum of the Military Medical Research Institute, a painting entitled "Rejection of Academicians" was displayed. The oil painting is about the story of the drug scientist Song Hongjun. At that time, Song Hongyi and others discovered a new structure of miraculous drugs, making China a world leader in certain types of drugs. The organization decided to declare his academician of the Chinese Academy of Sciences, but he insisted that he was not allowed because of the confidentiality of scientific research results.

For the country to keep secret, Song Hongyi was buried for 30 years. Until 2005, he died of illness, his achievements are still dusty.

Nothing to say, the motherland knows me. Indifferent to fame and fortune, only because the interests of the state and the military are seen more seriously.

The drug research and development market is highly profitable, and only the patent fees are very substantial. However, when a new type of antibiotic was developed, the Institute's experts asked companies not to mass produce for economic benefits, so as not to lose the last line of defense against super bacteria.

When the reporter left the interview and left the institute, he found that the training written on the wall was particularly eye-catching: the values ​​of fame and fortune, selfless dedication, the sense of responsibility for loyalty and loyalty, the attitude of life without arrogance, and the hard work. Careful, realistic and innovative research style... These simple and unpretentious words are filled with the spirit of a team of researchers who passed down from generation to generation. (Source: China Military Online Author: Li Jinhai Shaolong Fei Zhuangying Na)

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