As long as you eat a long-lived medicine that is brewed in the elder's alchemy furnace, the mortal can live forever. The myth in "Journey to the West" is now gradually becoming a reality. Wenzhou University reported today that the world's top comprehensive academic journal "Nature" has just published a result of the research team of the school's principal, Wenzhou Medical University - Wenzhou University Biomedical Collaborative Innovation Center, Professor Li Jiyao: Humans delay aging The password was further deciphered. This means that a major breakthrough has been made in a world puzzle that has plagued the life sciences for 20 years.

Since 1997, a "α-klotho" anti-aging protein that can participate in human body repair, regulation and regeneration has been discovered by scientists, scientific research in this field has been declared into the "α-klotho anti-aging research era". However, the anti-aging mechanism of this protein has always been called the "line of textile life" conjecture in the scientific community.

After nearly 10 years of research, the team of Li Xiaoxuan found that the anti-aging mechanism of “α-klotho” is that fibroblast growth factor 23 (FGF23) with senescence-regulating function is formed together with another member of the FGF family (FGFR1). The complex is assisted by the latter two. This latest discovery not only breaks through the world's leading scientific problems in human aging prevention research, but also reveals the law of the occurrence and development of aging-related diseases, and advances the development and research of world regenerative medicine.

According to Li Xiong, some members of the growth factor FGF family can participate in metabolic regulation, treat wound ulcers, promote the regeneration of damaged tissues, and promote the repair of aging and scar skin. Previous studies have shown that FGF23 is a key therapeutic target for chronic kidney disease. The study not only finds the “key” of anti-aging effects, but also provides a clear blueprint for the development of new kidney disease diagnostics and therapeutics.

At present, the Li School team is accelerating the development of new kidney disease diagnostic reagents and therapeutic drugs. This is also the first scientific research achievement in the world to develop the growth factor FGF into a new class of drugs. As of 2017, the three new drugs developed by the team have been applied to 80 million trauma patients in China, and they are important emergency treatment drugs for events such as the Wenchuan earthquake and the Tianjin Binhai explosion. (China Education News)

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