Our super green powder are mainly used as food supplement, health and wellness product additive, you can mix the super greens and Vegetable Powder according to your own formula. Spirulina, chlorella, broccoli powder, kale powder, buckwheat powder, wheatgrass powder, barley grass powder. Those powders are rich in protein, fibers, antioxidant and chlorophyll which can clear free radicals, enhance immunity and providing trace elements people can`t obtain from high carbohydrate diet. Organic super greens powders are Non-GMO, gluten free and vegan friendly, welcome to reach us for more you would like to know.
Super Greens,Buckwheat Grass,Organic Super Greens,Super Greens Powder YT(Xi'an) Biochem Co., Ltd. , https://www.ytnutra.com Large area disinfection
Health and safety
Story of two technologies
verification
Botox attack - hydrogen peroxide vapor disinfection in the dairy industry
New Zealand dairy giant Fonterra Co-operative Group Ltd. notified the New Zealand government on the 2nd that it had detected botulinum in three batches of concentrated whey protein, affecting three Chinese companies. Eight customers, including food giants such as Coca-Cola, Abbott, Danone, and Wahaha, were produced at a local factory in New Zealand last May, and the total amount of products suspected of being contaminated was 38 tons. The source of the pollution is an uncleaned pipeline from the company's Hotap plant in the Waikato area of ​​the North Island. So what is the danger of Botox? The relevant information can be found from Wikipedia as follows:
Bototridium botulinum is a Gram-positive bacterium that grows in normal temperature, low acid and anoxic environments. Botox can grow in canned foods or vacuum-packed foods that are improperly processed, packaged, and stored. Botox is widely distributed throughout nature, such as soil and animal waste. The gastrointestinal tract of the human body is also a good oxygen-deficient environment, which is very suitable for botulinum to live.
Botox spores are highly resistant, killing botulinum spores by drying at 180 ° C for 5-15 minutes, moist heat at 100 ° C for 5 hours, or high pressure steam at 121 ° C for 30 minutes. The optimum temperature for growth and reproduction of botulinum toxin is 18 to 30 °C. When the pH is below 4.5 or greater than 9.0, or when the ambient temperature is below 15 ° C or above 55 ° C, Clostridium botulinum spores are unable to multiply and produce no toxins. Therefore, both botulinum can be killed by heating and refrigeration. Botulinum toxin is not heat resistant, can be destroyed by heating at 75-85 ° C for 10 minutes or at 100 ° C for 1 minute.
The dairy crisis caused by a polluting pipeline has promoted the work of GMP, HACCP certification pilot and dairy product regionalization quality and safety, food protection plan, risk monitoring mechanism construction and credit system construction. The CFDA of the State Food and Drug Administration has further strengthened the supervision of the production of infant formula milk powder, not only announced the list of 128 infant formula milk powder enterprises, but also released the management model of the pharmaceutical company: “Enterprise production of infant formula milk powder license†The Conditions Review Rules (2013 Edition) (Draft for Comment) put forward higher requirements for production conditions and environment.
For the disinfection of the space in the dairy workshop, in order to prevent pollution and control the residue, ultraviolet or ozone disinfection is usually used, but there are certain limitations. Ultraviolet radiation reaches a certain intensity, although it can kill microorganisms well, but its light can only be direct, and it can't do anything for some backlights. Ozone disinfection can effectively reach all corners as an environmentally friendly and residual gas fumigation method. In a variety of food angry enterprises are all the rage, but the problem of using it for a long time has appeared, ozone is very corrosive to machinery and equipment, especially rubber products such as seals, and it will take a long time to replace the parts, and ozone is only a disinfectant. It is impossible to completely kill spores, which means that microbial spores can be revived once conditions are appropriate, requiring frequent repeated disinfection. So, is there no better means of disinfection? Of course, this is Hydrogen Peroxide Vapour Bio-decontamination, which is being used more and more in the pharmaceutical industry.
The use of hydrogen peroxide vapor HPV is not a new idea in the pharmaceutical industry. It has been used to sterilize sterile isolators for more than 15 years. You don't need to find a deeper reason to ask why, this is a beautifully simple technique, but requires superb control skills, not just a heating plate. . Regardless of the application, the liquid hydrogen peroxide solution needs to be flashed in a controlled manner to ensure uniform distribution of the vapor.
This steaming process continues until the appropriate sterilization conditions are reached and then maintained for a predetermined period of time. The final stage catalyzes the hydrogen peroxide vapor as a harmless decomposition product - water vapor and oxygen - to return the sterilization space to its original condition, but is already in a sterile state. This residue-free property is easy to verify, both in long and short cycles, and is compatible with materials, making the technology perfect.
Since the creation of the HPV sterilization concept, this technology has evolved from small closed systems such as isolators, transfer cabins, etc. to larger spaces such as rooms, suites, and even buildings. However, as the volume of disinfection expands and its unique settings pose challenges, a unique design of the building system is required for HPV sterilization. The resulting verification, health and safety issues need to be considered.
The initial hydrogen peroxide vapor sterilization focused on controlling the concentration of HPV throughout the process without exceeding the condensation point, as was done by using a drying cylinder to remove moisture from the environment before and during the cycle. This method is suitable for The adjustment of small-volume environmental conditions, but the problem of tens or hundreds of cubic meters of space, needless to say, limits the application of HPV in large volume.
Later studies have shown that this method is lower in sterilization efficiency than when the target space reaches the condensation point. It is found that when the concentration of the target environment reaches a peak during the cycle, it will not form a layer on the surface of all exposed objects. The sediment, under the microscope, is a condensed film of about 2 μm, which produces a more effective killing effect. Once the hydrogen peroxide molecules come into contact with the surface of the object, they immediately oxidize to form free radicals to attack the microorganisms, achieving a high level of sterilization (6-log spore killing rate) and a wide range of bacteria, spores, fungi, molds and viruses. effective spectrum, and we can have the opportunity to review as early as 2005 Johnston MD published an article on its 1,2 botulinum spores effectively kill.
Therefore, the elimination of restrictions on any environmental conditions is necessary to successfully perform large-area space disinfection, and there have been successful cases of nearly 3,500,000 cubic feet (99,100 cubic meters). Later, inspired by the direct injection of the sterilized room (the nozzle is usually placed in the center of the room, directly jetting HPV into the environment, that is, without the need to pass the filter), the sterilization of the isolator has also been newly developed. Hydrogen peroxide vapor is injected directly into the work area, rather than through efficient filtration of gas and exhaust, and the removal of environmental conditions limits, cycle time is completed within 1 hour, and is also evident in certain environments. Improved workflow.
As a disinfection method, the biggest reason for the development of hydrogen peroxide vapor technology in room disinfection applications is that the inherent concept (although incorrect) associates it with many of the drawbacks of formaldehyde fumigation.
In addition to becoming safer, disinfection has become more technological. Shown here is a mobile room disinfection device that vaporizes and vents hydrogen peroxide solution
From a safety point of view, these two technologies are very different, which is one of the reasons why formaldehyde fumigation is usually only used to deal with emergencies. When using formaldehyde, on-site preparation is usually carried out with as few people as possible, and the entire building needs to remain closed for many days to remove the scent of the monks. A large amount of manual cleaning is required to remove white powder residues, creating potential contaminants that pose a challenge to maintaining a sterile environment.
Compared to hydrogen peroxide vapor, the ward and operating room used in a general hospital can be sterilized in less than 90 minutes, and the general hospital infrastructure is far less sterilizable than most pharmaceutical companies, such as ceilings in the room, no The heating and ventilation device, the air conditioning system runs through the adjacent ward, and the disinfection area is only a stone's throw away from the public passage.
Why are the two technologies with the same purpose producing such a huge difference in safety? This is because it is harmful to humans to be exposed to a certain level of disinfectant gas. This concentration varies with different gases. Hydrogen peroxide vapor is currently the safest type, based on the OSHA Occupational Safety and Health Administration's allowable exposure limit (PEL) of 1 ppm, and the limit of acute hazard to life and health (IDLH) is 75 ppm. Formaldehyde is 0.5 ppm and 20 ppm.
At the same time, it is necessary to take into account the technical operability and environment to reach the limits of PEL and IDLH. Because of the hydrogen diffusion function (viscous molecules), the diffusivity of hydrogen peroxide vapor is poor, and this limitation can be overcome by nozzles with high kinetic energy. However, this poor diffusion has achieved its safety, because any leaks driven by external forces tend to remain in place. For formaldehyde, it spreads quickly because it is a normal gas, and the unfavorable side is to increase the risk of operator exposure.
This ability to remain in place is as simple as a few simple steps to prevent leaks, and it is important to have a hand-held sensor in the inspection. Operating conditions can be set to a negative pressure mode, and if a rare leak occurs when using hydrogen peroxide vapor, the operator has sufficient time to rearrange and seal the leak point. When using formaldehyde fumigation, the time to complete the same sealing work will be quite limited due to the low PEL limit and faster spreading capacity, and the occurrence of accidents using this technology has been documented. The target area is equipped with a wide range of sensors, combined with a hand-held sensor to determine if the target area is safe to re-enter after disinfection is complete.
It should be noted that chemicals such as formaldehyde spread quickly, but it does not mean that it is better or more thorough. These gas sterilization methods require a high humidity range - usually relative humidity is higher than 65%. To successfully complete the disinfection, the humidity value far exceeding the normal operating standard is required. This humidity is the content of water vapor, and its distribution becomes successful in disinfection. No restrictions.
It is important to verify and confirm the success of the disinfection. Regardless of the scope of application, the use of hydrogen peroxide vapor technology requires consideration of specific environmental factors such as size, structure and environmental conditions. These elements influence the performance of the entire disinfection cycle and can help determine a specific set of parameters for successful disinfection.
Although theoretical analysis can yield a reasonable starting parameter, it must be determined by running a loop development process. Once this set of parameters is completed within the security framework - and confirmed, the operation of a performance verification loop will result in the final verification loop.
The microbial challenge test for hydrogen peroxide application uses Geobacillus stearothermophilus, which requires a 6-log kill rate in a sterile operating environment. This microorganism is also widely recognized as a sterilization process and effect for steam autoclaving. Prove the challenge. 1
The advanced control system is built into the hydrogen peroxide steam generator, which is different from the various uncertainties in the use of formaldehyde. A continuous feedback loop process that is fully visualized by a variety of sensors, including interrupting, modifying, and abandoning operations when necessary. At the same time, highly automated production process control, in compliance with CFR Chapter 11 requirements, meets current Good Manufacturing Practice GMP requirements.
In summary, hydrogen peroxide vapor is obviously not only a substitute for formaldehyde and ozone, but because of its broad-spectrum sterilization efficiency, complete safety management characteristics and perfect process control, the whole process can be verified and supported. In the past, many new applications could be developed in the pharmaceutical and biotechnology fields.
The advantage of this technology is that it not only kills microorganisms in the area during the sterilization process, it can purify the entire production and processing environment, recover and upgrade to standard working conditions, in daily or emergency situations, peroxidation. Hydrogen vapor forms a new baseline process, and botulinum or similar events can rest.
Reference
1. Unger-Bimczok B, Kottke V, Hertel C, et al. The influence of humidity, hydrogen peroxide concentration, and condensation on the inactivation of Geobacillus stearothermophilus spores with hydrogen peroxide vapor. J Pharm Innov. 2008;3(2): 123-133.
2. Johnston MD, Lawson S, Otter JA. Evaluation of hydrogen peroxide vapour as a method for the decontamination of surfaces contaminated with Clostridium botulinum spores. J Microbiol Methods 2005;60(3):403-11.