The most continuous human genome assembly to date has been completed January 30, 2018 Source: Science and Technology Daily Fill in the "blind zone" that cannot be analyzed by previous sequencing methods The British journal Nature Biotechnology published a genomics study online on the 29th: the British team of scientists used a pocket-sized nanopore sequencing device to assemble the human genome from scratch, which is by far the most continuous human genome assembly. And only a single sequencing technology is used. The study also successfully analyzed the human genome regions that were not analyzed by the most advanced sequencing methods in the past. Understanding and interpreting the human genome is the cornerstone of modern medicine, and people have always wanted to sequence the genome as much as possible. Prior to this, the work was daunting due to various factors such as speed, cost and limited sequencing systems. Although sequencing techniques have improved, it is still challenging to assemble the human genome quickly and at low cost and to ensure high accuracy and integrity. This time, the University of Nottingham researchers Matthew Luther, Nicholas Roman and their colleagues used a portable bio-nanoparticle sequencer to sequence and assemble the human GM12878 cell line genome to generate a 91.2Gb sequence. data. Using this method, the single read length can be as long as 882 kb, enabling the research team to successfully analyze the "blind zone" that was not analyzed by the most advanced sequencing methods. It is a pity that there are unexplored regions in the genome, and sequencing unsequenced regions is the latest frontier in human genetics and genomics. The team said that this new method can detect structural and epigenetic modifications in the genome, filling 12 vacancies in the human reference genome GRCh38, thereby greatly improving its accuracy. (Reporter Zhang Mengran) Led Facial Mask,Led Light Facial Mask,Led Therapy Facial Mask,Led Facial Skin Care Mask Shenzhen Jie Zhong Lian Investment Co., Ltd. , https://www.szmeizonscares.com