The leeches contain hirudin, heparin and antithrombotic, which can be used for the treatment of cardiovascular and cerebrovascular diseases, tumors, etc., and are traditional and valuable Chinese medicinal materials. At present, common processing techniques include: raw drying method, water-scaling method, alkali burning method, drying method, drying method, and the like. The dried leeches processed by these methods have large internal biological activity damage, serious loss of active ingredients, and the quality of processing determines the price of leeches.

Advantages of vacuum freeze-drying leeches:

1. Sublimate 95%~99% moisture, and store it at room temperature for a long time after sealing;

2. Light weight, easy to transport and carry.

3. Drying is carried out at low temperature, and the functional components of leech are rarely lost. The thermosensitive substances such as proteins and cells are not easily deteriorated or damaged, and the biological activity is basically unchanged.

4. The leeches after lyophilization are loose and porous, with good rehydration and high efficacy.

Main factors and indicators for freeze-dried waterlogging:

1. Eutectic point: -22 ° C, pre-freezing at -22 ° C and below;

2. Co-melting point: -15 ° C, the temperature of the material during the sublimation drying process must be lower than -15 ° C. However, sublimation drying is a dynamic process. As the water in the leech decreases, the concentration of leech increases. In this process, the eutectic point of the leech increases with the structure and water content of the leech.

3. In the pre-freezing stage, the stepwise cooling method is adopted to reduce the temperature difference between the shelf and the water raft, and the freezing speed of the water raft is slowed down, so as to improve the sublimation speed;

4. In the analytical drying stage, the temperature difference between the shelf and the water raft is reduced by means of a stepwise heating method to facilitate the control of the drying speed.

The whole process of freeze-drying water rafts using the vacuum freeze dryer produced by Henan Brother Instrument Equipment Co., Ltd. is carried out under low temperature (-27~30 °C) and low pressure conditions. The obtained lyophilized lyophilized powder has the characteristics of less loss of biologically active substance, low water content of the finished product, and good preservation of color, shape and active ingredients.

Advantages of leeches freeze dryer:

Square warehouse in-situ vacuum freeze dryer, pre-freezing, drying in situ

Internationally renowned brand compressors, dual-machine cascade refrigeration, high efficiency, energy saving, long service life and low noise.

Silicone heating function: stainless steel shelf has low viscosity silicone oil medium circulation control lifting temperature, high temperature control accuracy, shelf temperature difference ≤ 1 ° C, uniform drying effect.

A 7-inch industrial embedded LCD touch screen displays cold trap temperature, sample temperature, shelf temperature, and vacuum.

Standard anti-return oil vacuum pump with oil mist filter, the ultimate vacuum can reach 5pa.

PLC control system with high reliability and stability.

The patented gas guiding technology has a uniform trap for ice trapping and a strong ice trapping capability.

Temperature fuzzy control system, the shelf rise and temperature reduction rate can be controlled under the slope control state.

It adopts a safety diaphragm valve, which can be connected to an inert gas source. After drying, it is filled with inert gas to extend the shelf life of the material.

The control system is professionally designed to store hundreds of freeze-drying process recipes. Each recipe can be set with 36 temperature control sections to improve process optimization.

It can query historical curve and history, and can modify the storage cycle and data record U disk export in real time.

Technical indicators:

Freeze-drying area: 1.04m2

Material plate size: 475 × 355mm

Number of material trays: 6

Shelf size: 480 × 360mm

Number of shelves: 6+1 floors

Shelf spacing: 70mm

Shelf temperature range: -50 ° C ~ +70 ° C

Shelf temperature difference: ±1 °C

Cold trap temperature: ≤ -80 ° C (no load)

Water catching capacity: ≥15KG/24h

Pumping rate: 15L/S

Ultimate vacuum: ≤5pa (no load)

Installed power: 6500w

Host weight: 700kg

Mainframe dimensions: 1170×830×1665mm

Cooling method: air cooling

Panel material: 10L