Inquiries: Experts Hello, I planted mycelium mushroom bag cultivation mycelium had just made brown coffee on the edge of the lid, and later became pink, what is the reason?

Answer: According to the symptoms of this mushroom farmer, it was basically able to determine that the mushroom was infected with Neurospora sp. Because of the very typical symptoms of orange-red or pink powdery mildew after infection with this fungus, other bacteria do not.

There may be three ways to cause the initial infection of this symptom: 1. The strains carry the bacteria; 2. The culture carrier strains are not completely disinfected; 3. The germs room has such bacteria.

Secondly, talk about several characteristics of Trichoderma:

1. The mycelia of Nalesporium grew fastest at 25°C to 36°C, and grew slowly below 24°C, and was not affected by relative humidity, so it was prone to occur in summer and autumn. 2. The optimum pH of hyphae is 5.0-7.5, so it prefers to grow and spread on acidic media. 3. Rapid growth, rapid proliferation and great harm. When the conditions are suitable, the surface of the culture material can be covered within 2 to 3 days, and the hyphae of the edible fungus compete for nutrition, moisture, and space, which often causes pollution and scrapping of the entire batch of culture material.

At present, the mushroom farmer should take measures to grasp the bag in a special confined space and pour out the infected part of it deeply buried or burned. The remaining raw materials are poured out and collected in the sun for 10 days or so. They are used after the new ingredients are mixed in next time. At the same time, several comprehensive prevention and control measures are described based on the primary characteristics of the primary infestation source and the bacteria:

1. Do a good job of environmental hygiene. Vaccination room, bacteria room, and mushroom shed must be disinfected in a timely manner.

2. Strictly select strains. When you purchase bacteria, you must check it strictly because the symptoms are typical and can be basically found through visual inspection. In addition, if there is no elimination by visual inspection, bacterial strains infected with bacteria are found to be handled in a timely manner.

3. Select a good quality, no microporous bag. When the bag hole or crack is found, stick it with tape.

4. Add 0.1% 50% carbendazim wettable powder during the seasoning; at the same time, the amount of lime should be properly increased during the season of high-temperature seasoning, and the culture materials should be used with the mix to prevent acidity; standard operations should be performed during sterilization. Ensure sterilization effect.

Key Intermediates

Intermediate – Intermediate: A material produced during a drug substance processing step that must undergo further molecular modification or refinement to become a drug substance. Intermediates may or may not be isolated. Intermediates are the key products of the previous process of making APIs, which are different in structure from APIs.

Ceftriaxone sodium powder is called preparation, sterile ceftriaxone sodium is called API, and 7-ACA is called intermediate.

Our company specializes in providing key intermediates for various APIs

Intermediate is a very important type of fine chemical products. Its essence is a type of "semi-finished product", which is an intermediate product in the production of certain products. For example, if a product is to be produced, it can be produced from intermediates, saving costs and reducing It is widely used in the synthesis of medicines, pesticides, coatings, dyes and spices. In the field of medicine, intermediates are an important link in the industrial chain of the pharmaceutical industry. They are used for some chemical raw materials or chemical products in the process of drug synthesis. In a word, they are used to produce APIs.

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