Release date: 2015-12-16 The application of 3D printing technology or bio-printing technology in biomedicine has always been the world's attention, because once this breakthrough in research, it is likely to have a revolutionary impact on the future of mankind. Although most of these studies will take years to complete, there have been some very interesting research results. For example, a team of scientists from Melbourne, Australia, recently achieved truly groundbreaking achievements: They successfully printed the cortical tissue block in 3D, which is a kind of brain tissue. The result was obtained by a team of scientists at the University of Melbourne's Neuroengineering Center, whose head Stan Skanfidas has expressed optimism about these small cell clumps. The brain tissue is made from human stem cells, and scientists used a special 3D bioprinter in the center to form six layers of brain tissue by printing. According to Tiangong, the brain cells that form the tissue have been able to connect and communicate with each other, and they even form a folded structure that is identical to the original brain structure. The project's research team includes engineers, neuroscientists, doctors, and computer experts. Professor Skafidas said that although this is only a preliminary success, it has brought the dawn of treatment to restore the brain function of patients, such as the treatment of autism and schizophrenia. And a wider range of neurological diseases are likely to benefit from this success. Until now, research on this type of disease has often relied on animal experiments. This breakthrough may mean that scientists can easily culture patients' brain tissue samples and then first test the effectiveness of the drugs on these samples. "There is a hypothesis that schizophrenia and autism are caused by inflammation in the mother's early pregnancy," the professor said. “We can simulate this condition in a Petri dish to see how it affects brain development.†Yes, it will take a while for these devices to become reality. The brain tissue that scientists have 3D printed (smaller than peas) died in 30 days due to lack of blood and oxygen. The next step for the researchers is to extend their survival to 100 days. This requires the team to develop new technologies that can deliver oxygen and nutrients to cells. "If there is a suitable microbial environment, the tissue block will begin to form a brain, which may be equivalent to the brain of a 20-30 day fetus," the professor said. Moreover, because the brain cells in the 3D printed tissue have formed networks and connections, scientists can begin to study the interactions between some genes in the brain - these may lead to some common diseases. In short, its potential impact is multifaceted. As Professor Skafidas claims, this research opens the way for scientists to learn more about the most mysterious parts of the human body. “Now is the 21st century, but we still don’t know how the brain works,†Professor Skafidas said. Source: Tiangongshe
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