Porcine salmonellosis, commonly referred to as piglet paratyphoid fever, is a conditional infectious disease in weaned piglets caused by pathogenic Salmonella. Acute cases are sepsis changes, and chronic cases are large intestinal necroinflammation and pneumonia. The disease occurs mostly in 2-4 months old piglets, no seasonality, as long as the temperature difference changes greatly, the pig house density is large, can be ill, but rarely seen in adult pigs. Porcine salmonellosis has occurred in pig farms all over the country, especially in pig farms with poor sanitary conditions. This disease often occurs, causing great losses to the breeding industry. Below we will specifically understand what is the prevention and treatment of swine salmonellosis and after the onset of illness. Porcine salmonellosis is a common disease caused by Salmonella bacteria. It is sporadic and endemic, and is a common infectious disease in piglets. If there is a sudden change in climate, rain and rain, coupled with lack of feeding and management conditions, it is more likely to cause the disease. In addition, the pig's stocking density is too large, or the stress of the transfer group, the intervention of other infectious diseases will increase the detoxification of the pigs and the susceptibility of the pigs. After the pathogen continues to pass more animals, its virulence will become stronger and stronger, and then the spread of infection will occur. Treatment measures after onset (1) Isolation of sick pigs and timely treatment. Furazolidone (Metring), chloramphenicol, and sulfonamides can all be used for treatment. No matter what method is adopted, it is necessary to insist on improving the combination of feeding management and sanitary conditions in order to receive satisfactory results. (2) The house should be cleaned and disinfected regularly, especially the feeding trough should be cleaned frequently. The feces are accumulated and fermented for use. (3) According to the circumstances of the epidemic at the time of onset, if necessary, it is assumed that healthy pigs can be supplemented with ç—¢ç‰¹çµ or antibiotic feed in the feed. (4) Dead pigs should be buried deeply and must not be eaten to prevent people from getting poisoning accidents. I. Differential diagnosis and analysis of swine salmonellosis (1) Clinical symptoms and pathological changes of swine salmonellosis Under normal circumstances, pigs with porcine salmonellosis, the body temperature of the pig will reach 40-41.5 ° C, manifested as depression, diarrhea, lack of energy, chills and loss of appetite, etc., the stool is grayish yellow liquid, stench. The pig's eye has sticky secretions, and purple-red spots appear on the chest, the roots of the ears, and under the abdomen, making it difficult to breathe. Many sick pigs die within 3 days of illness. Anatomy of the sick pig, you can see the subcutaneous edema of the corpse, there are a large number of bleeding points, and the submandibular lymph nodes are large, the spleen is swollen, the color is dark blue, there are a lot of bleeding points and necrotic foci. There are also some gray-yellow necrotic spots in the liver parenchyma, hepatomegaly, congestion, and hemorrhage. The kidney is swollen, the capsule is easy to peel off, there are a lot of bleeding points, the gastrointestinal mucosa shows spotted hemorrhage, and pleural effusion appears. There is a large amount of liquid in the pig intestine, necrotic enteritis in the intestine, and a diffuse bran-like necrotic pseudomembrane on the mucosal surface. The pseudomembrane can be peeled off to have a red irregular ulcer surface on the edge. (II) Laboratory differential diagnosis of porcine salmonellosis Liver, blood and mesenteric lymph node smears of pigs with swine porcine disease were taken, and Gram-negative bacteria with blunt ends were observed by Gram staining. Salmonella porcine was cultured for 24 hours at a temperature of 37 ° C. The MacConkey agar had colorless transparent round small colonies with a diameter of about 1 mm. It is round, smooth and moist on ordinary nutrient agar, and its edges are neat, and the translucent dew-like wet grayish white colonies with a diameter of about 1 mm. Pick a typical colony staining microscopy and see small Gram-negative bacteria. When cultured with nutrient broth, it showed a uniform turbidity and a small amount of sediment at the bottom of the tube. 2. Differential diagnosis and analysis of swine salmonellosis and swine lung disease Porcine lung disease, also known as porcine Pasteurellosis, is a rapid heat-borne infection caused by Pasteurella multocida. The disease and pig salmonellosis can also cause high temperature, diarrhea, difficulty breathing, and skin. Bleeding spots, eczema, etc. However, pig lung disease can occur in all ages of pigs. Many animals are likely to be infected, usually in the late stage of endemic epidemics. Before the disease turns into a slow-moving disease, there are throat type and chest type, and the necropsy can be performed. Seeing the lung consolidation zone gradually increased, there appeared grayish yellow and gray necrotic foci, which contained cheese-like substances, and the chest cavity was filled with cellulose. The pigs with swine lung disease were examined by necropsy. The main lesions were systemic mucosa and subcutaneous tissue hemorrhage. There is a large amount of light yellow exudate under the skin, major bleeding in the submandibular lymph nodes, a large amount of foamy mucus can be seen in the gas and bronchus, and there are obvious blister-like ridges on the sides of the tongue and the sides of the tonsils. There are emphysema, edema, erythema and hemorrhagic symptoms in the lungs, as well as necrosis of tofu-like slag, bleeding in the small intestine mucosa and stomach, bladder bleeding, and swollen lymph nodes. Third, the differential diagnosis of swine salmonellosis and swine fever Hog Cholera is a highly contagious viral infection caused by swine fever virus with high morbidity and mortality. The clinical similarity between swine fever and swine salmonellosis is that the sick pigs have high body temperature, high contagiousness, purple-red spots on the skin, and diarrhea. The difference between swine salmonellosis and swine fever is that pig swine bacillosis mainly occurs in piglets from January to April. The incidence rate is not high in piglets, and the mucous membranes are severely inflamed, the spleen is swollen, and there are margins and sizes. A necrotic foci. In the clinical practice, the swine fever is usually characterized by constipation and squatting. The pig's eye has secretions, and the gastric mucosa has symptoms of punctate hemorrhage. The skin often has smaller bleeding points. The sick pig spirit is more depressed, does not eat, and the drug treatment has no effect. Pigs of different ages will develop symptoms. The pigs with swine fever were dissected, the liver and spleen were not swollen, there was no necrosis, the spleen had hemorrhagic infarction, and there was a mouth ulcer near the ileocecal mouth. In clinical practice, swine fever is characterized by small vessel wall degeneration, and at the same time, it causes bleeding, necrosis and other diseases in various organs and tissues. Porcine salmonellosis is a typical four-season disease, which is typical of clinical symptoms of slow-moving cases. The diagnosis of the disease can be combined with the symptoms and pathology of the disease. As the disease continues to develop, many common diseases have also developed mixed infections, especially in pigs with initial infections. Porcine salmonellosis is not untreated. According to industry insiders, after the disease occurs, if the measures taken are properly taken, effective control can be obtained to minimize the loss. The disease is focused on prevention, daily breeding, and keeping pigs. The clean and ventilated house will reduce the incidence of this disease. Antiparasitic Veterinary Drug,Veterinary Drug Apis,Bulk Drug Dimetridazole,Raw Material Medicine Powder NANYANG CHENGPENG PHARMACEUTICAL CO.,LTD , https://www.chppharm.com
