How far is precision medicine from us?

A patient with fever, diarrhea, and difficulty in breathing was diagnosed with severe pneumonia by the hospital. The cost of medication per day was close to 1,500 yuan, but the condition was getting heavier. When using a chip test, the hospital found a clear source of infection, and used erythromycin, which cost only 10 yuan a day, and was quickly cured.

On June 25th, at the World Future Science and Technology Forum held in Chengdu, when Cheng Jing, an academician of the Chinese Academy of Engineering and a professor at Tsinghua University Medical School, spoke of this precise medical case, it caused a sigh of audience.

How far is precision medicine from us – a question that makes ordinary people curious and has been fully discussed in this forum. Cheng Jing said that if we can quickly, easily and accurately detect, people do not have to go to the top three hospitals frequently, and can greatly reduce the burden on the top three hospitals.

China's precision medicine is catching up with international standards

When you are pregnant with your child, how can you know if your child has hearing problems? The child passed the hearing screening when he was born, but after two or three years, his hearing gradually declined, and his parents were caught off guard. How can this situation be prevented?

These problems of hereditary deafness and delayed deafness, Cheng Jing's team has achieved a successful "precise detection." He said that before we couldn't know who would face this problem, we can know ahead of time through the gene chip.

Human problems discovered through gene chips can guide people's real life, such as deciding how to use drugs or even decide whether two people are suitable for marriage and children. Cheng Jing said that some antibiotics can cause delayed deafness. If the test finds such a situation, the doctor can issue a list of banned antibiotics to the patient. Each time you see the doctor, you can avoid the medication. deaf.

He also cites, for example, if a disease is found to be maternally inherited by genetic chip testing, which means that this mother can give birth to both the boy and the girl, but the boy will not inherit it any more, while the girl will still inherit it. It is possible to inherit.

"If both men and women carry a recessive cariogenic gene, check it in advance before marriage, because there is a 25% chance of giving birth to a hearing-impaired child, but a 75% chance of giving birth to a healthy child." Cheng Jing said.

There are very few cases of precision medical success for some complex diseases.

Kang Guixia, a professor at Beijing University of Posts and Telecommunications, believes that precision medicine is a wonderful blueprint. Through accurate analysis and treatment, human health can be guaranteed. "Everyone is not a dream when they live 100 years old."

But this blueprint is still facing many challenges. Ji Jianxin, executive vice president of the Dio Group, believes that the current precision medicine is more directed at genetic diseases, and some infectious diseases and diseases such as tumors, cardiovascular and cerebrovascular diseases, and where precision medicine can exert strength are still limited. Successful cases very few.

Shi Hubing, a researcher at the State Key Laboratory of Biotherapy at West China Hospital of Sichuan University, believes that the biggest problem facing precision medical care at present is the cost issue. “We want to screen suspicious individuals at the lowest cost in the shortest amount of time, and now it’s 'no cost'.”

Ji Jianxin believes that precision medicine is now more focused on accurate detection, helping people to recognize the health risks that may be faced in the future, and after accurate detection, what is needed is how to conduct precise intervention.

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