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The traditional drying techniques of traditional Chinese medicine extracts are mainly electric oven drying and ordinary vacuum drying. However, due to the high viscosity and poor gas permeability of traditional Chinese medicine extracts. In order to obtain better drying effect, the temperature of the extract in the drying process generally needs to reach 80 cI=above, and the drying time is long. Therefore, the above drying techniques all have low yield, high energy consumption, low production efficiency and low product quality. Disadvantages. At present, new drying techniques such as spray drying and vacuum freeze drying have been promoted and applied in the drying process of traditional Chinese medicine extracts, but there are still some defects and limitations for traditional Chinese medicine extracts with high viscosity and high sugar content. The promotion and application of new vacuum belt drying technology has played a positive role in improving the quality and improving the stability of traditional Chinese medicine extracts.
Common techniques for drying traditional Chinese medicine extract
Van drying
Box drying is an early and simple drying method, and is still widely used in the drying of traditional Chinese medicine extracts. There are heating pipes on both sides of the box. The tray is placed on the shelf inside the box, or placed directly on the shelf made of steam exhaust pipe, with a vent hole at the top or an exhaust fan to discharge the moisture. The heated plate in the vacuum oven is divided into several layers. The heating plate is filled with hot water or low-pressure steam as a heating medium, and the tray on which the medicine to be dried is placed is placed on a heating plate, and a vacuum pump is used to evacuate the inside of the box. The heating plate heats the drug to a specified temperature in a circulating flow of the heating medium. The moisture of the material is evaporated and withdrawn by vacuuming.
The drying of the van is characterized by its simplicity and applicability, and is generally applicable to flammable, viscous, thixotropic or paste materials. The drug is not easily contaminated during the drying process and can be used for drying the drug, sterilization of the packaging material and heat treatment. However, van drying also has many defects. For example, high labor intensity, high calorie consumption, low thermal efficiency (thermal energy utilization is less than 40%), and long drying time, causing some heat-sensitive components to decompose and the quality of the drug is reduced. During the drying process, the material is easy to form into a hard block and is difficult to crush.
In the 1980s, van drying was the main drying method in the API industry. The van type drying is suitable for the drying of small batches and multi-variety materials. Therefore, the drying equipment of different sizes is installed in the laboratory, the intermediate test factory and the factory. With the introduction of a variety of new dryers, van dryers are gradually being replaced by other drying techniques. Most of the van dryers reserved by Chinese medicine companies are now improved. Many drying equipment manufacturers have developed a series of van dryers suitable for the drying of traditional Chinese medicine extracts. For example, the through-flow oven produced by Changzhou Chuangxie Machinery Co., Ltd. can effectively prevent the entrained materials in the air from deteriorating during the cycle and reheating process. Contamination of drugs. The medicinal GMP type oven overcomes the shortcomings that the traditional oven cannot fully comply with the GMP pharmaceutical production specifications, and has a high heat transfer coefficient, good heat utilization rate, and short material drying time. In addition, improved van driers such as hot air circulation ovens are still commonly used in the drying of traditional Chinese medicine extracts.
Research progress on drying technology of traditional Chinese medicine extract: chamber drying
Drying is an important part in the production of traditional Chinese medicine preparations. It is widely used in the production of pharmaceutical auxiliary materials, raw materials, intermediates and finished products. The quality of drying operations directly affects the performance, quality, appearance and cost of the products. The application of drying technology in the Chinese medicine industry has a long history, but it has only been widely recognized and developed very well in the past 20 years.